產(chǎn)品詳情
簡單介紹：
Anti-FIG4 antibody (608-907) (STJ117567)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-FIG4 (608-907) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:200-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FIG4 |
| Gene ID: | 9896 |
| Uniprot ID: | FIG4_HUMAN |
| Immunogen Region: | 608-907 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 608-907 of human FIG4 (NP_055660.1). |
| Immunogen Sequence: | WELPTDFYLHHKNTMRLLPT RRSYTYWWTPEVIKHLPLPY DEVICAVNLKKLIVKKFHKY EEEIDIHNEFFRPYELSSFD DTFCLAMTSSARDFMPKTVG IDPSPFTVRKPDETGKSVLG NKSNREEAVLQRKTAASAPP PPSEEAVSSSSEDDSGTDRE EEGSVSQRSTPVKMTDAGDS AKVTENVVQPMKELYGINLS DGLSEEDFSIYSRFVQLGQS QHKQDKNSQQPCSRCSDGV |
| Function | Dual specificity phosphatase component of the PI(3,5)P2 regulatory complex which regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the dephosphorylation of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) to form phosphatidylinositol 3-phosphate. Has serine-protein phosphatase activity acting on PIKfyve to stimulate its lipid kinase activity, its catalytically activity being required for maximal PI(3,5)P2 production. In vitro, hydrolyzes all three D5-phosphorylated polyphosphoinositide and although displaying preferences for PtdIns(3,5)P2, it is capable of hydrolyzing PtdIns(3,4,5)P3 and PtdIns(4,5)P2, at least in vitro. |
| Protein Name | Polyphosphoinositide Phosphatase Phosphatidylinositol 3 -5-Bisphosphate 5-Phosphatase Sac Domain-Containing Protein 3 Serine-Protein Phosphatase Fig4 |
| Database Links | Reactome: R-HSA-1660514 Reactome: R-HSA-1660516 Reactome: R-HSA-1660517 |
| Cellular Localisation | Endosome Membrane Localization Requires Vac14 And Pikfyve |
| Alternative Antibody Names | Anti-Polyphosphoinositide Phosphatase antibody Anti-Phosphatidylinositol 3 -5-Bisphosphate 5-Phosphatase antibody Anti-Sac Domain-Containing Protein 3 antibody Anti-Serine-Protein Phosphatase Fig4 antibody Anti-FIG4 antibody Anti-KIAA0274 antibody Anti-SAC3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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