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產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：Anti-FCER2 antibody (222-321) [S0MR] (STJ11101330)

  • 產(chǎn)品型號(hào)：STJ11101330
  • 產(chǎn)品廠(chǎng)商：ST john's laboratory
  • 產(chǎn)品文檔：
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Anti-FCER2 antibody (222-321) [S0MR] (STJ11101330)
詳情介紹：
Host: Rabbit
Applications: WB/IF
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-CD23 (222-321) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: S0MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FCER2
Gene ID: 2208
Uniprot ID: FCER2_HUMAN
Immunogen Region: 222-321
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 222-321 of human CD23 (P06734).
Immunogen Sequence: GLRNLDLKGEFIWVDGSHVD YSNWAPGEPTSRSQGEDCVM MRGSGRWNDAFCDRKLGAWV CDRLATCTPPASEGSAESMG PDSRPDPDGRLPTPSAPLHS
Post Translational Modifications N- and O-glycosylated. The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding.
Function Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway.
Protein Name Low Affinity Immunoglobulin Epsilon Fc Receptor
Blast-2
C-Type Lectin Domain Family 4 Member J
Fc-Epsilon-Rii
Immunoglobulin E-Binding Factor
Lymphocyte Ige Receptor
Cd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form
Database Links Reactome: R-HSA-2197563
Reactome: R-HSA-6783783
Reactome: R-HSA-6785807
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Lipid-Anchor
Secreted
Also Exists As A Soluble Excreted Form
Scd23
Alternative Antibody Names Anti-Low Affinity Immunoglobulin Epsilon Fc Receptor antibody
Anti-Blast-2 antibody
Anti-C-Type Lectin Domain Family 4 Member J antibody
Anti-Fc-Epsilon-Rii antibody
Anti-Immunoglobulin E-Binding Factor antibody
Anti-Lymphocyte Ige Receptor antibody
Anti-Cd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form antibody
Anti-FCER2 antibody
Anti-CD23A antibody
Anti-CLEC4J antibody
Anti-FCE2 antibody
Anti-IGEBF antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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