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產(chǎn)品詳情

  • 產(chǎn)品名稱：Anti-F11 antibody (491-540 aa) (STJ193904)

  • 產(chǎn)品型號(hào)：STJ193904
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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Anti-F11 antibody (491-540 aa) (STJ193904)
詳情介紹：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Coagulation factor XI (491-540 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: F11
Gene ID: 2160
Uniprot ID: FA11_HUMAN
Immunogen Region: 491-540 aa
Specificity: This antibody detects endogenous levels of FA11 at Human/Mouse
Immunogen: Synthesized peptide derived from the human FA11 at the amino acid range 491-540
Post Translational Modifications N-glycosylated on both chains. N-glycosylated sites mainly consist of nonfucosylated sialylated biantennary (in high abundance) and/or triantennary (in low abundance) complex structures. Glycosylation at Asn-163 uses a rare non-canonical Asn-X-Cys glycosite. Activated by factor XIIa (or XII), which cleaves each polypeptide after Arg-387 into the light chain, which contains the active site, and the heavy chain, which associates with high molecular weight (HMW) kininogen.
Function Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
Protein Name Coagulation Factor Xi
Fxi
Plasma Thromboplastin Antecedent
Pta Cleaved Into - Coagulation Factor Xia Heavy Chain - Coagulation Factor Xia Light Chain
Database Links Reactome: R-HSA-140837
Reactome: R-HSA-9673221
Cellular Localisation Secreted
Alternative Antibody Names Anti-Coagulation Factor Xi antibody
Anti-Fxi antibody
Anti-Plasma Thromboplastin Antecedent antibody
Anti-Pta Cleaved Into - Coagulation Factor Xia Heavy Chain - Coagulation Factor Xia Light Chain antibody
Anti-F11 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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