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產(chǎn)品詳情

  • 產(chǎn)品名稱：Mouse TARC (Thymus Activation Regulated Chemokine) CLIA Kit (STJC0001015)

  • 產(chǎn)品型號(hào)：STJC0001015
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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Mouse TARC (Thymus Activation Regulated Chemokine) CLIA Kit (STJC0001015)
詳情介紹：
Applications: CLIA
Reactivity: Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Sensitivity: 7.5pg/mL
Detection Limit: 12.5~800pg/mL
Short Description: This mouse TARC kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
Storage Instruction: If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time: 3.5h
Detection: Chemiluminescence
Gene Symbol: Ccl17
Gene ID: 20295
Uniprot ID: CCL17_MOUSE
Specificity: This kit recognizes Mouse TARC in samples. No significant cross-reactivity or interference between Mouse TARC and analogues was observed.
Sample Type: Serum, plasma and other biological fluids
Tissue Specificity Expressed in primary and secondary lymphoid organs, where it is specifically produced by a subset of dendritic cells. Not expressed in the spleen. Constitutively expressed in thymus, as well as in the lung, skin and intestine. Not expressed in bone marrow-derived macrophages and activated B cells, nor in thymocytes. In the brain, predominantly expressed in a subset of hippocampal CA1 neurons.
Function Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. May be important for the appropriate adaptation of microglial morphology and synaptic plasticity to acute lipopolysaccharide (LPS)-induced neuroinflammation. Plays a role in wound healing, mainly by inducing fibroblast migration into the wound.
Protein Name C-C Motif Chemokine 17
Abcd-2
Cc Chemokine Tarc
Small-Inducible Cytokine A17
Thymus And Activation-Regulated Chemokine
Cellular Localisation Secreted
Alternative CLIA Names C-C Motif Chemokine 17 CLIA kit
Abcd-2 CLIA kit
Cc Chemokine Tarc CLIA kit
Small-Inducible Cytokine A17 CLIA kit
Thymus And Activation-Regulated Chemokine CLIA kit
Ccl17 CLIA kit
Tarc CLIA kit
Specificity This kit recognizes Mouse TARC in samples. No significant cross-reactivity or interference between Mouse TARC and analogues was observed.
Reproducibility Both intra-CV and inter-CV are

Information sourced from Uniprot.org


Item Specifications Storage
Micro CLIA Plate (Dismountable) 96T: 8 wells ×12 strips strips -20℃, 6 months
Reference Standard 96T: 2 vials 48T: 1 vial -20℃, 6 months
Concentrated Biotinylated Detection Ab (100×) 96T: 1 vial, 120 μL 60 μL -20℃, 6 months
Concentrated HRP Conjugate (100×) 96T: 1 vial, 120 μL 60 μL -20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent 1 vial, 20 mL 2-8°C, 6 months
Biotinylated Detection Ab Diluent 1 vial, 14 mL 2-8°C, 6 months
HRP Conjugate Diluent 1 vial, 14 mL 2-8°C, 6 months
Concentrated Wash Buffer (25×) 1 vial, 30 mL 2-8°C, 6 months
Substrate Reagent A 1 vial, 5 mL 2-8℃ (Protect from light)
Substrate Reagent B 1 vial, 5 mL 2-8℃ (Protect from light)
Plate Sealer 5 pieces
Manual 1 copy
Certificate of Analysis 1 copy

Sample Type Range (%) Average Recovery (%)
Serum(n=8) 96-108 101
EDTA plasma(n=8) 91-107 98
Cell culture media(n=8) 88-103 95

Intra-assay Precision Intra-assay Precision Intra-assay Precision Inter-assay Precision Inter-assay Precision Inter-assay Precision
Sample 1.00 2.00 3.00 1.00 2.00 3.00
n 20.00 20.00 20.00 20.00 20.00 20.00
Mean (pg/mL) 37.72 95.02 388.96 40.69 93.99 376.66
Standard deviation 3.61 7.08 43.95 4.03 10.63 42.68
CV (%) 9.57 7.45 11.30 9.90 11.31 11.33
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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