產(chǎn)品詳情
簡單介紹：
Anti-EXT1 antibody (467-746) (STJ23589)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-EXT1 (467-746) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 IF/ICC 1:50-1:200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EXT1 |
| Gene ID: | 2131 |
| Uniprot ID: | EXT1_HUMAN |
| Immunogen Region: | 467-746 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 467-746 of human EXT1 (NP_000118.2). |
| Immunogen Sequence: | YYYANLGLKPPSKFTAVIHA VTPLVSQSQPVLKLLVAAAK SQYCAQIIVLWNCDKPLPAK HRWPATAVPVVVIEGESKVM SSRFLPYDNIITDAVLSLDE DTVLSTTEVDFAFTVWQSFP ERIVGYPARSHFWDNSKERW GYTSKWTNDYSMVLTGAAIY HKYYHYLYSHYLPASLKNMV DQLANCEDILMNFLVSAVTK LPPIKVTQKKQYKETMMGQT SRASRWADPDHFAQRQSCM |
| Tissue Specificity | Ubiquitous. |
| Function | Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan. |
| Protein Name | Exostosin-1 Glucuronosyl-N-Acetylglucosaminyl-Proteoglycan/N-Acetylglucosaminyl-Proteoglycan 4-Alpha-N-Acetylglucosaminyltransferase Multiple Exostoses Protein 1 Putative Tumor Suppressor Protein Ext1 |
| Database Links | Reactome: R-HSA-2022928 Reactome: R-HSA-3656237 Reactome: R-HSA-3656253 |
| Cellular Localisation | Endoplasmic Reticulum Membrane Single-Pass Type Ii Membrane Protein Golgi Apparatus Membrane Golgi Apparatus Cis-Golgi Network Membrane The Ext1/Ext2 Complex Is Localized In The Golgi Apparatus |
| Alternative Antibody Names | Anti-Exostosin-1 antibody Anti-Glucuronosyl-N-Acetylglucosaminyl-Proteoglycan/N-Acetylglucosaminyl-Proteoglycan 4-Alpha-N-Acetylglucosaminyltransferase antibody Anti-Multiple Exostoses Protein 1 antibody Anti-Putative Tumor Suppressor Protein Ext1 antibody Anti-EXT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
相關(guān)信息
![Anti-14-3-3 beta/Theta antibody (1-100) [S1MR] (STJ11103651)](http://y1.yzimgs.com/uploads/465546/2024520-20551366.png?imageView2/2/w/200/h/200)
- 細(xì)胞培養(yǎng)玄學(xué)-MRC-5細(xì)胞 2025-01-07
- Ocean NanoTech定制的詳細(xì)步驟 2021-10-31
- click chemistry tools數(shù)據(jù)結(jié)果比... 2021-10-31
- LaysanBio代理商相關(guān)文獻(xiàn)資料2020 2021-10-31
- Abbiotec代理的產(chǎn)品得到重復(fù)驗(yàn)證2020 2021-10-31
- zyagen Laboratories代理的產(chǎn)品得到... 2021-06-20
- Toxin Technologies代理商相關(guān)文獻(xiàn)資... 2021-03-14
- 熱烈祝賀玉博生物正式代理biocolor公司試劑產(chǎn)品... 2021-03-14
- 熱烈祝賀玉博生物正式代理cytognos公司試劑產(chǎn)品... 2021-03-14
- Gelest代理的產(chǎn)品得到重復(fù)驗(yàn)證2020 2021-03-14
