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產(chǎn)品詳情

  • 產(chǎn)品名稱：Mouse Pgp (Permeability Glycoprotein) Sandwich ELISA Kit (STJE0011439)

  • 產(chǎn)品型號：STJE0011439
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡單介紹：
Mouse Pgp (Permeability Glycoprotein) Sandwich ELISA Kit (STJE0011439)
詳情介紹：
Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.051ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This Pgp Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Abcb1b
Gene ID: 18669
Uniprot ID: MDR1B_MOUSE
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications Several phosphorylated serine residues are present in the linker domain.
Function Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Protein Name Atp-Dependent Translocase Abcb1
Atp-Binding Cassette Sub-Family B Member 1b
Multidrug Resistance Protein 1b
P-Glycoprotein 1
Phospholipid Transporter Abcb1
Cd Antigen Cd243
Database Links
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Apical Cell Membrane
Cytoplasm
Abcb1 Localization Is Influenced By C1orf115 Expression Levels (Plasma Membrane Versus Cytoplasm)
Alternative ELISA Names Atp-Dependent Translocase Abcb1 ELISA kit
Atp-Binding Cassette Sub-Family B Member 1b ELISA kit
Multidrug Resistance Protein 1b ELISA kit
P-Glycoprotein 1 ELISA kit
Phospholipid Transporter Abcb1 ELISA kit
Cd Antigen Cd243 ELISA kit
Abcb1b ELISA kit
Abcb1 ELISA kit
Mdr1 ELISA kit
Mdr1b ELISA kit
Pgy1 ELISA kit
Pgy1-1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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