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產(chǎn)品詳情

  • 產(chǎn)品名稱：Anti-DENND4A antibody (1500-1650) (STJ118535)

  • 產(chǎn)品型號(hào)：STJ118535
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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Anti-DENND4A antibody (1500-1650) (STJ118535)
詳情介紹：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DENND4A (1500-1650) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DENND4A
Gene ID: 10260
Uniprot ID: MYCPP_HUMAN
Immunogen Region: 1500-1650
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1500-1650 of human DENND4A (NP_005839.3).
Immunogen Sequence: RPGRYFLKSSPSTENMHFPS SISSQTRQSCISTSASGLDT SALSVQGNFDLNSKSKLQEN FCTRSIQIPANRSKTAMSKC PIFPMARSISTSGPLDKEDT GRQKLISTGSLPATLQGATD SLGLEWHLPSPDPVTVPYLS PLVVWKELESL
Tissue Specificity Expressed ubiquitously. Highest expression in bone marrow, medium in peripheral blood lymphocytes and lowest in spleen. In brain, breast, and prostate, higher expression was seen in normal cells than in tumor cells. Expression is regulated in a growth- and cell cycle-dependent manner.
Function Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter.
Protein Name C-Myc Promoter-Binding Protein
Denn Domain-Containing Protein 4a
Database Links Reactome: R-HSA-8876198
Cellular Localisation Nucleus
Alternative Antibody Names Anti-C-Myc Promoter-Binding Protein antibody
Anti-Denn Domain-Containing Protein 4a antibody
Anti-DENND4A antibody
Anti-IRLB antibody
Anti-MYCPBP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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