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產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：Anti-ACSL5 antibody (500-739) (STJ116065)

  • 產(chǎn)品型號(hào)：STJ116065
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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Anti-ACSL5 antibody (500-739) (STJ116065)
詳情介紹：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ACSL5 (500-739) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ACSL5
Gene ID: 51703
Uniprot ID: ACSL5_HUMAN
Immunogen Region: 500-739
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 500-739 of human ACSL5 (NP_057318.2).
Immunogen Sequence: GQTECTGGCTFTLPGDWTSG HVGVPLACNYVKLEDVADMN YFTVNNEGEVCIKGTNVFKG YLKDPEKTQEALDSDGWLHT GDIGRWLPNGTLKIIDRKKN IFKLAQGEYIAPEKIENIYN RSQPVLQIFVHGESLRSSLV GVVVPDTDVLPSFAAKLGVK GSFEELCQNQVVREAILEDL QKIGKESGLKTFEQVKAIFL HPEPFSIENGLLTPTLKAKR GELSKYFRTQIDSLYEHIQ
Function Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage. Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids. It was suggested that it may also stimulate fatty acid oxidation. At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL. May have a role in the survival of glioma cells.
Protein Name Long-Chain-Fatty-Acid--Coa Ligase 5
Arachidonate--Coa Ligase
Long-Chain Acyl-Coa Synthetase 5
Lacs 5
Database Links Reactome: R-HSA-75876
Cellular Localisation Mitochondrion
Endoplasmic Reticulum
Mitochondrion Outer Membrane
Single-Pass Type Iii Membrane Protein
Endoplasmic Reticulum Membrane
Cell Membrane
Alternative Antibody Names Anti-Long-Chain-Fatty-Acid--Coa Ligase 5 antibody
Anti-Arachidonate--Coa Ligase antibody
Anti-Long-Chain Acyl-Coa Synthetase 5 antibody
Anti-Lacs 5 antibody
Anti-ACSL5 antibody
Anti-ACS5 antibody
Anti-FACL5 antibody
Anti-UNQ633 antibody
Anti-PRO1250 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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