產(chǎn)品詳情
簡單介紹：
Anti-ACSL4 antibody (1-280) (STJ11103869)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IHC/IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Long-Chain-Fatty-Acid--Coa Ligase 4 (1-280) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:100-1:500 IHC-P 1:50-1:200 IF/ICC 1:50-1:200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ACSL4 |
| Gene ID: | 2182 |
| Uniprot ID: | ACSL4_HUMAN |
| Immunogen Region: | 1-280 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ACSL4 (NP_004449.1). |
| Immunogen Sequence: | MAKRIKAKPTSDKPGSPYRS VTHFDSLAVIDIPGADTLDK LFDHAVSKFGKKDSLGTREI LSEENEMQPNGKVFKKLILG NYKWMNYLEVNRRVNNFGSG LTALGLKPKNTIAIFCETRA EWMIAAQTCFKYNFPLVTLY ATLGKEAVVHGLNESEASYL ITSVELLESKLKTALLDISC VKHIIYVDNKAINKAEYPEG FEIHSMQSVEELGSNPENLG IPPSRPTPSDMAIVMYTSG |
| Function | Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially activates arachidonate and eicosapentaenoate as substrates. Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET. Modulates glucose-stimulated insulin secretion by regulating the levels of unesterified EETs. Modulates prostaglandin E2 secretion. |
| Protein Name | Long-Chain-Fatty-Acid--Coa Ligase 4 Arachidonate--Coa Ligase Long-Chain Acyl-Coa Synthetase 4 Lacs 4 |
| Database Links | Reactome: R-HSA-434313 Reactome: R-HSA-75876 |
| Cellular Localisation | Mitochondrion Outer Membrane Single-Pass Type Iii Membrane Protein Peroxisome Membrane Microsome Membrane Endoplasmic Reticulum Membrane Cell Membrane |
| Alternative Antibody Names | Anti-Long-Chain-Fatty-Acid--Coa Ligase 4 antibody Anti-Arachidonate--Coa Ligase antibody Anti-Long-Chain Acyl-Coa Synthetase 4 antibody Anti-Lacs 4 antibody Anti-ACSL4 antibody Anti-ACS4 antibody Anti-FACL4 antibody Anti-LACS4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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