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產(chǎn)品詳情
  • 產(chǎn)品名稱:Dystrophin Blocking Peptide for STJ507807 peptide (STJ507810)

  • 產(chǎn)品型號:STJ507810-250
  • 產(chǎn)品廠商:ST john's laboratory
  • 產(chǎn)品文檔:
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簡單介紹:
Dystrophin Blocking Peptide for STJ507807 peptide (STJ507810)
詳情介紹:
Applications: Immunodepletion/Immunocompetition
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Dystrophin Blocking Peptide for STJ507807 is synthetically produced from the 200-250 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: DMD
Gene ID: 1756
Uniprot ID: DMD_HUMAN
Immunogen Region: 200-250
Specificity: This blocking peptide is recommended for use in combination with Dystrophin antibody, STJ507807
Immunogen: Synthetic peptide corresponding to amino acids within region 200-250 on rat 5-hydroxytrptamine receptor 1A protein.
Function Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission.
Peptide Name Dystrophin
Database Links Reactome: R-HSA-3000171
Reactome: R-HSA-390522
Cellular Localisation Cell Membrane
Sarcolemma
Peripheral Membrane Protein
Cytoplasmic Side
Cytoplasm
Cytoskeleton
Postsynaptic Cell Membrane
In Muscle Cells
Sarcolemma Localization Requires The Presence Of Ank2
While Localization To Costameres Requires The Presence Of Ank3
Localizes To Neuromuscular Junctions (Nmjs)
In Adult Muscle
Nmj Localization Depends Upon Ank2 Presence
But Not In Newborn Animals
Alternative Peptide Names Dystrophin protein
DMD protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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