產(chǎn)品詳情
簡單介紹:
Dystrophin Blocking Peptide for STJ507807 peptide (STJ507810)
詳情介紹:
Applications: | Immunodepletion/Immunocompetition |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Dystrophin Blocking Peptide for STJ507807 is synthetically produced from the 200-250 sequence and is suitable for use in western blot applications. |
Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | DMD |
Gene ID: | 1756 |
Uniprot ID: | DMD_HUMAN |
Immunogen Region: | 200-250 |
Specificity: | This blocking peptide is recommended for use in combination with Dystrophin antibody, STJ507807 |
Immunogen: | Synthetic peptide corresponding to amino acids within region 200-250 on rat 5-hydroxytrptamine receptor 1A protein. |
Function | Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission. |
Peptide Name | Dystrophin |
Database Links | Reactome: R-HSA-3000171 Reactome: R-HSA-390522 |
Cellular Localisation | Cell Membrane Sarcolemma Peripheral Membrane Protein Cytoplasmic Side Cytoplasm Cytoskeleton Postsynaptic Cell Membrane In Muscle Cells Sarcolemma Localization Requires The Presence Of Ank2 While Localization To Costameres Requires The Presence Of Ank3 Localizes To Neuromuscular Junctions (Nmjs) In Adult Muscle Nmj Localization Depends Upon Ank2 Presence But Not In Newborn Animals |
Alternative Peptide Names | Dystrophin protein DMD protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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