印度肥婆丰满bbw,娇乳欲女h奶汁翘,漂亮人妻办公室里沦陷,日韩Aⅴ人妻无码一区二区

產(chǎn)品詳情

  • 產(chǎn)品名稱：DYRK1 Positive Control peptide (STJ505503)

  • 產(chǎn)品型號：STJ505503-5
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
你添加了1件商品 查看購物車
簡單介紹：
DYRK1 Positive Control peptide (STJ505503)
詳情介紹：
Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: DYRK1 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: DYRK1A
Gene ID: 1859
Uniprot ID: DYR1A_HUMAN
Tissue Specificity Ubiquitous. Highest levels in skeletal muscle, testis, fetal lung and fetal kidney.
Post Translational Modifications Autophosphorylated on numerous tyrosine residues. Can also autophosphorylate on serine and threonine residues (in vitro).
Function Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Exhibits a substrate preference for proline at position P+1 and arginine at position P-3. Plays an important role in double-strand breaks (DSBs) repair following DNA damage. Mechanistically, phosphorylates RNF169 and increases its ability to block accumulation of TP53BP1 at the DSB sites thereby promoting homologous recombination repair (HRR). Also acts as a positive regulator of transcription by acting as a CTD kinase that mediates phosphorylation of the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A. May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Modulates alternative splicing by phosphorylating the splice factor SRSF6. Has pro-survival function and negatively regulates the apoptotic process. Promotes cell survival upon genotoxic stress through phosphorylation of SIRT1. This in turn inhibits p53/TP53 activity and apoptosis. Phosphorylates SEPTIN4, SEPTIN5 and SF3B1 at 'Thr-434'.
Peptide Name Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase 1a
Dual Specificity Yak1-Related Kinase
Hp86
Protein Kinase Minibrain Homolog
Mnbh
Hmnb
Database Links Reactome: R-HSA-1538133
Cellular Localisation Nucleus
Nucleus Speckle
Alternative Peptide Names Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase 1a protein
Dual Specificity Yak1-Related Kinase protein
Hp86 protein
Protein Kinase Minibrain Homolog protein
Mnbh protein
Hmnb protein
DYRK1A protein
DYRK protein
MNB protein
MNBH protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
電話：
您的需求：
 

滬公網(wǎng)安備 31011002002624號