產(chǎn)品詳情
簡單介紹:
DRIP130 Positive Control peptide (STJ504450)
詳情介紹:
Applications: | WB |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | DRIP130 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
Dilution Range: | WB: 1:500 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | MED23 |
Gene ID: | 9439 |
Uniprot ID: | MED23_HUMAN |
Function | Required for transcriptional activation subsequent to the assembly of the pre-initiation complex. Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. Required for transcriptional activation by adenovirus E1A protein. Required for ELK1-dependent transcriptional activation in response to activated Ras signaling. |
Peptide Name | Mediator Of Rna Polymerase Ii Transcription Subunit 23 Activator-Recruited Cofactor 130 Kda Component Arc130 Cofactor Required For Sp1 Transcriptional Activation Subunit 3 Crsp Complex Subunit 3 Mediator Complex Subunit 23 Protein Sur-2 Homolog Hsur-2 Transcriptional Coactivator Crsp130 Vitamin D3 Receptor-Interacting Protein Complex 130 Kda Component Drip130 |
Database Links | Reactome: R-HSA-1989781 Reactome: R-HSA-212436 Reactome: R-HSA-381340 |
Cellular Localisation | Nucleus |
Alternative Peptide Names | Mediator Of Rna Polymerase Ii Transcription Subunit 23 protein Activator-Recruited Cofactor 130 Kda Component protein Arc130 protein Cofactor Required For Sp1 Transcriptional Activation Subunit 3 protein Crsp Complex Subunit 3 protein Mediator Complex Subunit 23 protein Protein Sur-2 Homolog protein Hsur-2 protein Transcriptional Coactivator Crsp130 protein Vitamin D3 Receptor-Interacting Protein Complex 130 Kda Component protein Drip130 protein MED23 protein ARC130 protein CRSP3 protein DRIP130 protein KIAA1216 protein SUR2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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