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產品名稱：DRIP130 Blocking Peptide peptide (STJ504368)
產品型號：STJ504368-250
產品廠商：ST john's laboratory
產品文檔：

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簡單介紹：

DRIP130 Blocking Peptide peptide (STJ504368)

詳情介紹：

Applications:	Immunodepletion/Immunocompetition
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	DRIP130 Blocking Peptide is synthetically produced from the 650-700 sequence and is suitable for use in western blot applications.

Formulation:	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	MED23
Gene ID:	9439
Uniprot ID:	MED23_HUMAN
Immunogen Region:	650-700
Immunogen:	Synthetic pepetide taken within amino acid region 650-700 on MED23 protein.

Function	Required for transcriptional activation subsequent to the assembly of the pre-initiation complex. Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. Required for transcriptional activation by adenovirus E1A protein. Required for ELK1-dependent transcriptional activation in response to activated Ras signaling.
Peptide Name	Mediator Of Rna Polymerase Ii Transcription Subunit 23 Activator-Recruited Cofactor 130 Kda Component Arc130 Cofactor Required For Sp1 Transcriptional Activation Subunit 3 Crsp Complex Subunit 3 Mediator Complex Subunit 23 Protein Sur-2 Homolog Hsur-2 Transcriptional Coactivator Crsp130 Vitamin D3 Receptor-Interacting Protein Complex 130 Kda Component Drip130
Database Links	Reactome: R-HSA-1989781 Reactome: R-HSA-212436 Reactome: R-HSA-381340
Cellular Localisation	Nucleus
Alternative Peptide Names	Mediator Of Rna Polymerase Ii Transcription Subunit 23 protein Activator-Recruited Cofactor 130 Kda Component protein Arc130 protein Cofactor Required For Sp1 Transcriptional Activation Subunit 3 protein Crsp Complex Subunit 3 protein Mediator Complex Subunit 23 protein Protein Sur-2 Homolog protein Hsur-2 protein Transcriptional Coactivator Crsp130 protein Vitamin D3 Receptor-Interacting Protein Complex 130 Kda Component protein Drip130 protein MED23 protein ARC130 protein CRSP3 protein DRIP130 protein KIAA1216 protein SUR2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：DRIP130 Blocking Peptide peptide (STJ504368)