產(chǎn)品詳情
簡單介紹：
Dopamine Transporter Positive Control peptide (STJ503970)
詳情介紹：
| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Dopamine Transporter Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: | WB: 1:500 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | SLC6A3 |
| Gene ID: | 6531 |
| Uniprot ID: | SC6A3_HUMAN |
| Tissue Specificity | Highly expressed in substantia nigra. Expressed in axonal varicosities in dopaminergic nerve terminals (at protein level). Expressed in the striatum (at protein level). |
| Function | Mediates sodium- and chloride-dependent transport of dopamine. Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline). Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling. |
| Peptide Name | Sodium-Dependent Dopamine Transporter Da Transporter Dat Solute Carrier Family 6 Member 3 |
| Database Links | Reactome: R-HSA-379401 Reactome: R-HSA-442660 Reactome: R-HSA-5619081 Reactome: R-HSA-5660724 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Cell Projection Neuron Projection Axon Localizes To Neurite Tips In Neuronal Cells Colocalizes With Septin4 At Axon Terminals Especially At The Varicosities |
| Alternative Peptide Names | Sodium-Dependent Dopamine Transporter protein Da Transporter protein Dat protein Solute Carrier Family 6 Member 3 protein SLC6A3 protein DAT1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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