產(chǎn)品詳情
簡單介紹:
Dopamine D2 Receptor Positive Control for STJ500708 peptide (STJ503966)
詳情介紹:
Applications: | WB |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Dopamine D2 Receptor Positive Control for STJ500708 is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
Dilution Range: | WB: 1:1, 000-1:1, 5000 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | DRD2 |
Gene ID: | 1813 |
Uniprot ID: | DRD2_HUMAN |
Specificity: | This is positive control is recommended for use in combination with Dopamine D2 Receptor antibody STJ500708. |
Tissue Specificity | Isoform 1: Expressed in the anterior pituitary gland. Isoform 2: Expressed in the anterior pituitary gland. |
Post Translational Modifications | Palmitoylated. Palmitoylation which is required for proper localization to the plasma membrane and stability of the receptor could be carried on by ZDHHC4, ZDHHC3 and ZDHHC8. |
Function | Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5. |
Peptide Name | D(2 Dopamine Receptor Dopamine D2 Receptor |
Database Links | Reactome: R-HSA-390651 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Golgi Apparatus Membrane |
Alternative Peptide Names | D(2 Dopamine Receptor protein Dopamine D2 Receptor protein DRD2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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