產(chǎn)品詳情
簡單介紹：
DOC2B Positive Control for STJ500788 peptide (STJ503980)
詳情介紹：
| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | DOC2B Positive Control for STJ500788 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: | WB: 1:500 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Doc2b |
| Gene ID: | 81820 |
| Uniprot ID: | DOC2B_RAT |
| Specificity: | This is positive control is recommended for use in combination with DOC2B antibody STJ500788. |
| Tissue Specificity | Expressed in brain.highly enriched in neurons. |
| Function | Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes. |
| Peptide Name | Double C2-Like Domain-Containing Protein Beta Doc2-Beta |
| Cellular Localisation | Cytoplasm Cytoplasmic Granule Cell Membrane Peripheral Membrane Protein Translocates To The Plasma Membrane In A Calcium-Dependent Manner |
| Alternative Peptide Names | Double C2-Like Domain-Containing Protein Beta protein Doc2-Beta protein Doc2b protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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