產(chǎn)品詳情
簡單介紹:
Human DNER protein (Recombinant) (C-hFc&His) (STJP001002)
詳情介紹:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human DNER-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
Gene Symbol: | DNER |
Gene ID: | 92737 |
Uniprot ID: | DNER_HUMAN |
Immunogen Region: | Arg29-His637 |
Immunogen: | Recombinant Human DNER Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Arg29-His637) of human DNER (Accession #NP_620711.3) fused with an Fc, 6×His tag at the C-terminus. |
Tissue Specificity | Expressed in brain, spinal cord and adrenal gland. |
Function | Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis. |
Protein Name | Delta And Notch-Like Epidermal Growth Factor-Related Receptor |
Database Links | Reactome: R-HSA-2122948 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein Present On The Membrane Of Dendrites And Cell Bodies But Excluded From Axonal Membrane Also Found In Early Endosomes In The Somatodendritic Region |
Alternative Protein Names | Delta And Notch-Like Epidermal Growth Factor-Related Receptor protein DNER protein BET protein UNQ262 protein PRO299 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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