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產(chǎn)品詳情
  • 產(chǎn)品名稱:Human DLL4 protein (Recombinant) (C-His & Avi) (STJP002140)

  • 產(chǎn)品型號:STJP002140-100
  • 產(chǎn)品廠商:ST john's laboratory
  • 產(chǎn)品文檔:
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簡單介紹:
Human DLL4 protein (Recombinant) (C-His & Avi) (STJP002140)
詳情介紹:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human DLL4-C-His & Avi protein was developed from hek293 cells and has a target region of C-His & Avi. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DLL4
Gene ID: 54567
Uniprot ID: DLL4_HUMAN
Immunogen Region: Ser27-Pro524
Immunogen: Recombinant Human DLL4 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Ser27-Pro524) of Human DLL4 fused with a His tag at the C-terminal.
Function Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis.negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.
Protein Name Delta-Like Protein 4
Drosophila Delta Homolog 4
Delta4
Database Links Reactome: R-HSA-2122948
Reactome: R-HSA-2644606
Reactome: R-HSA-2660826
Reactome: R-HSA-2691232
Reactome: R-HSA-2894862
Reactome: R-HSA-2979096
Reactome: R-HSA-9013507
Reactome: R-HSA-9013700
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Delta-Like Protein 4 protein
Drosophila Delta Homolog 4 protein
Delta4 protein
DLL4 protein
UNQ1895 protein
PRO4341 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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