產(chǎn)品詳情
簡(jiǎn)單介紹:
Human Cystatin-M/CST6 protein (Recombinant) (C-His) (STJP002603)
詳情介紹:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human Cystatin-M/CST6-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Immunoreactivity: | Measured by its ability to inhibit papain cleavage of a fluorogenic peptide substrate Z-FR-AMC. The IC50 value is approximately 16 nM. |
Gene Symbol: | CST6 |
Gene ID: | 1474 |
Uniprot ID: | CYTM_HUMAN |
Immunogen Region: | Arg29-Met149 |
Immunogen: | Recombinant Human Cystatin-M/CST6 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Arg29-Met149) of human CST6 (Accession #NP_001314.1) fused with a 6×His tag at the C-terminus. |
Post Translational Modifications | Substrate for transglutaminases. Acts as an acyl acceptor but not as an acyl donor. |
Function | High affinity inhibitor for cathepsin L, cathepsin L2 (cathepsin V), and legumain. Involved in the regulation of epidermal cornification, and hair follicle morphogenesis and maintenance. |
Protein Name | Cystatin-M Cystatin-6 Cystatin-E |
Cellular Localisation | Secreted |
Alternative Protein Names | Cystatin-M protein Cystatin-6 protein Cystatin-E protein CST6 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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