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產(chǎn)品詳情

  • 產(chǎn)品名稱：Anti-ACOX1 antibody (1-270) (STJ110391)

  • 產(chǎn)品型號(hào)：STJ110391
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡單介紹：
Anti-ACOX1 antibody (1-270) (STJ110391)
詳情介紹：
Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ACOX1 (1-270) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:100-1:500
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ACOX1
Gene ID: 51
Uniprot ID: ACOX1_HUMAN
Immunogen Region: 1-270
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ACOX1 (NP_004026.2).
Immunogen Sequence: MNPDLRRERDSASFNPELLT HILDGSPEKTRRRREIENMI LNDPDFQHEDLNFLTRSQRY EVAVRKSAIMVKKMREFGIA DPDEIMWFKNFVHRGRPEPL DLHLGMFLPTLLHQATAEQQ ERFFMPAWNLEIIGTYAQTE MGHGTHLRGLETTATYDPET QEFILNSPTVTSIKWWPGGL GKTSNHAIVLAQLITKGKCY GLHAFIVPIREIGTHKPLPG ITVGDIGPKFGYDEIDNGY
Tissue Specificity Widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tissue and testis. Levels are almost equal in heart.
Function Involved in the initial and rate-limiting step of peroxisomal beta-oxidation of straight-chain saturated and unsaturated very-long-chain fatty acids. Catalyzes the desaturation of fatty acyl-CoAs such as palmitoyl-CoA (hexadecanoyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs) such as (2E)-hexadecenoyl-CoA, and donates electrons directly to molecular oxygen (O(2)), thereby producing hydrogen peroxide (H(2)O(2)). Isoform 1: Shows highest activity against medium-chain fatty acyl-CoAs. Shows optimum activity with a chain length of 10 carbons (decanoyl-CoA) in vitro. Isoform 2: Is active against a much broader range of substrates and shows activity towards long-chain fatty acyl-CoAs.
Protein Name Peroxisomal Acyl-Coenzyme A Oxidase 1
Aox
Palmitoyl-Coa Oxidase
Peroxisomal Fatty Acyl-Coa Oxidase
Straight-Chain Acyl-Coa Oxidase
Scox Cleaved Into - Peroxisomal Acyl-Coa Oxidase 1 - A Chain - Peroxisomal Acyl-Coa Oxidase 1 - B Chain - Peroxisomal Acyl-Coa Oxidase 1 - C Chain
Database Links Reactome: R-HSA-1989781 Q15067-1
Reactome: R-HSA-2046106 Q15067-2
Reactome: R-HSA-390247 Q15067-2
Reactome: R-HSA-9033241
Reactome: R-HSA-9033500
Cellular Localisation Peroxisome
Alternative Antibody Names Anti-Peroxisomal Acyl-Coenzyme A Oxidase 1 antibody
Anti-Aox antibody
Anti-Palmitoyl-Coa Oxidase antibody
Anti-Peroxisomal Fatty Acyl-Coa Oxidase antibody
Anti-Straight-Chain Acyl-Coa Oxidase antibody
Anti-Scox Cleaved Into - Peroxisomal Acyl-Coa Oxidase 1 - A Chain - Peroxisomal Acyl-Coa Oxidase 1 - B Chain - Peroxisomal Acyl-Coa Oxidase 1 - C Chain antibody
Anti-ACOX1 antibody
Anti-ACOX antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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