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產(chǎn)品名稱：Anti-ACOT8 antibody (1-220) (STJ115034)
產(chǎn)品型號：STJ115034
產(chǎn)品廠商：ST john's laboratory
產(chǎn)品文檔：

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簡單介紹：

Anti-ACOT8 antibody (1-220) (STJ115034)

詳情介紹：

Host:	Rabbit
Applications:	WB
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-ACOT8 (1-220) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ACOT8
Gene ID:	10005
Uniprot ID:	ACOT8_HUMAN
Immunogen Region:	1-220
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ACOT8 (NP_005460.2).
Immunogen Sequence:	MSSPQAPEDGQGCGDRGDPP GDLRSVLVTTVLNLEPLDED LFRGRHYWVPAKRLFGGQIV GQALVAAAKSVSEDVHVHSL HCYFVRAGDPKLPVLYQVER TRTGSSFSVRSVKAVQHGKP IFICQASFQQAQPSPMQHQF SMPTVPPPEELLDCETLIDQ YLRDPNLQKRYPLALNRIAA QEVPIEIKPVNPSPLSQLQR MEPKQMFWVRARGYIGEGDM

Tissue Specificity	Detected in a T-cell line (at protein level). Ubiquitous.
Function	Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Displays no strong substrate specificity with respect to the carboxylic acid moiety of Acyl-CoAs. Hydrolyzes medium length (C2 to C20) straight-chain, saturated and unsaturated acyl-CoAS but is inactive towards substrates with longer aliphatic chains. Moreover, it catalyzes the hydrolysis of CoA esters of bile acids, such as choloyl-CoA and chenodeoxycholoyl-CoA and competes with bile acid CoA:amino acid N-acyltransferase (BAAT). Is also able to hydrolyze CoA esters of dicarboxylic acids. It is involved in the metabolic regulation of peroxisome proliferation. (Microbial infection) May mediate Nef-induced down-regulation of CD4 cell-surface expression.
Protein Name	Acyl-Coenzyme A Thioesterase 8 Acyl-Coa Thioesterase 8 Choloyl-Coenzyme A Thioesterase Hiv-Nef-Associated Acyl-Coa Thioesterase Peroxisomal Acyl-Coa Thioesterase 2 Pte-2 Peroxisomal Acyl-Coenzyme A Thioester Hydrolase 1 Pte-1 Peroxisomal Long-Chain Acyl-Coa Thioesterase 1 Thioesterase Ii Hacte-Iii Hacteiii Hte
Database Links	Reactome: R-HSA-193368 Reactome: R-HSA-2046106 Reactome: R-HSA-389887 Reactome: R-HSA-390247 Reactome: R-HSA-9033241
Cellular Localisation	Peroxisome Matrix Predominantly Localized In The Peroxisome But A Localization To The Cytosol Cannot Be Excluded
Alternative Antibody Names	Anti-Acyl-Coenzyme A Thioesterase 8 antibody Anti-Acyl-Coa Thioesterase 8 antibody Anti-Choloyl-Coenzyme A Thioesterase antibody Anti-Hiv-Nef-Associated Acyl-Coa Thioesterase antibody Anti-Peroxisomal Acyl-Coa Thioesterase 2 antibody Anti-Pte-2 antibody Anti-Peroxisomal Acyl-Coenzyme A Thioester Hydrolase 1 antibody Anti-Pte-1 antibody Anti-Peroxisomal Long-Chain Acyl-Coa Thioesterase 1 antibody Anti-Thioesterase Ii antibody Anti-Hacte-Iii antibody Anti-Hacteiii antibody Anti-Hte antibody Anti-ACOT8 antibody Anti-ACTEIII antibody Anti-PTE1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產(chǎn)品名稱：Anti-ACOT8 antibody (1-220) (STJ115034)