產(chǎn)品詳情
簡單介紹：
Human CD226 (DNAM-1) protein (Recombinant) (STJP000612)
詳情介紹：
| Host: | HEK293 |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Recombinant-Human CD226 (DNAM-1)-protein was developed from hek293. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/μg (1EU/μg). NA |
| Immunoreactivity: | Recombinant Human CD226 activity was measured using Immobilized Human CD226 at 2 Mu g/ml ability to bind biotinylated Human CD112 with a linear ranger of 0.06-0.8 Mu g/ml NA |
| Gene Symbol: | CD226 |
| Gene ID: | 10666 |
| Uniprot ID: | CD226_HUMAN |
| Immunogen Region: | ECD |
| Immunogen: | Optimized DNA sequence encoding extracellular domain of HumanCD226 (DNAM-1) including a C-terminal His tag was expressed in HEK293 cells. NA |
| Tissue Specificity | Expressed by peripheral blood T-lymphocytes. |
| Function | Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding. |
| Protein Name | Cd226 Antigen Dnax Accessory Molecule 1 Dnam-1 Cd Antigen Cd226 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
| Alternative Protein Names | Cd226 Antigen protein Dnax Accessory Molecule 1 protein Dnam-1 protein Cd Antigen Cd226 protein CD226 protein DNAM1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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