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產(chǎn)品名稱(chēng)：Human CD200R1 protein (Active Recombinant) (C-hFc&His) (STJP001358)
產(chǎn)品型號(hào)：STJP001358
產(chǎn)品廠(chǎng)商：ST john's laboratory
產(chǎn)品文檔：

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Human CD200R1 protein (Active Recombinant) (C-hFc&His) (STJP001358)

詳情介紹：

Host:	HEK293 cells
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Active Recombinant-Human CD200R1-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications.

Formulation:	Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Immunoreactivity:	Measured by its binding ability in a functional ELISA. Immobilized Human CD200 at 2 Mu g/mL (100 Mu L/well) can bind Human CD200 R with a linear range of 0.058-8.34 ng/mL.

Gene Symbol:	CD200R1
Gene ID:	131450
Uniprot ID:	MO2R1_HUMAN
Immunogen:	Recombinant Human CD200R1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala27-Leu266) of human CD200R/MOX2R (Accession #NP_620161.1) fused with a Fc, 6×His tag at the C-terminus.

Function	Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.
Protein Name	Cell Surface Glycoprotein Cd200 Receptor 1 Cd200 Cell Surface Glycoprotein Receptor Cell Surface Glycoprotein Ox2 Receptor 1
Database Links	Reactome: R-HSA-198933
Cellular Localisation	Isoform 1: Cell Membrane Single-Pass Type I Membrane Protein Isoform 4: Cell Membrane Isoform 2: Secreted Isoform 3: Secreted
Alternative Protein Names	Cell Surface Glycoprotein Cd200 Receptor 1 protein Cd200 Cell Surface Glycoprotein Receptor protein Cell Surface Glycoprotein Ox2 Receptor 1 protein CD200R1 protein CD200R protein CRTR2 protein MOX2R protein OX2R protein UNQ2522 protein PRO6015 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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