產(chǎn)品詳情
簡(jiǎn)單介紹:
Anti-Acetyl-H2AZ1-K5 antibody (1-50 aa) (STJ90117)
詳情介紹:
Host: | Rabbit |
Applications: | IHC/IF/WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Acetyl-Histone H2A.Z-K5 (1-50 aa) is suitable for use in Immunohistochemistry, Immunofluorescence, Western Blot and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 IHC 1:100-1:300 ELISA 1:5000 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | H2AZ1 |
Gene ID: | 3015 |
Uniprot ID: | H2AZ_HUMAN |
Immunogen Region: | 1-50 aa |
Specificity: | Acetyl-Histone H2A (K5) Polyclonal Antibody detects endogenous levels of Histone H2A protein only when acetylated at K5. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human Histone H2A around the acetylated site of Lys5 at the amino acid range 1-50 |
Function | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division. |
Protein Name | Histone H2a.z H2a/Z |
Database Links | Reactome: R-HSA-977225 |
Cellular Localisation | Nucleus Chromosome |
Alternative Antibody Names | Anti-Histone H2a.z antibody Anti-H2a/Z antibody Anti-H2AZ1 antibody Anti-H2AFZ antibody Anti-H2AZ antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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