產(chǎn)品詳情
簡單介紹：
CD10 Blocking Peptide peptide (STJ504409)
詳情介紹：
| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | CD10 Blocking Peptide is synthetically produced from the 200-250 sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | MME |
| Gene ID: | 4311 |
| Uniprot ID: | NEP_HUMAN |
| Immunogen Region: | 200-250 |
| Immunogen: | Synthetic peptide taken within amino acid region 200-250 on human Neprilysin protein. |
| Post Translational Modifications | Myristoylation is a determinant of membrane targeting. Glycosylation at Asn-628 is necessary both for surface expression and neutral endopeptidase activity. |
| Function | Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Catalyzes cleavage of bradykinin, substance P and neurotensin peptides. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1-32)). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. |
| Peptide Name | Neprilysin Atriopeptidase Common Acute Lymphocytic Leukemia Antigen Calla Enkephalinase Neutral Endopeptidase 24.11 Nep Neutral Endopeptidase Skin Fibroblast Elastase Sfe Cd Antigen Cd10 |
| Database Links | Reactome: R-HSA-2022377 Reactome: R-HSA-5578768 Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell Membrane Single-Pass Type Ii Membrane Protein |
| Alternative Peptide Names | Neprilysin protein Atriopeptidase protein Common Acute Lymphocytic Leukemia Antigen protein Calla protein Enkephalinase protein Neutral Endopeptidase 24.11 protein Nep protein Neutral Endopeptidase protein Skin Fibroblast Elastase protein Sfe protein Cd Antigen Cd10 protein MME protein EPN protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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