產(chǎn)品詳情
簡單介紹:
Human CCL13/MCP-4 protein (Recombinant) (C-hFc) (STJP001828)
詳情介紹:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human CCL13/MCP-4-C-hFc protein was developed from hek293 cells and has a target region of C-hFc. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CCL13 |
Gene ID: | 6357 |
Uniprot ID: | CCL13_HUMAN |
Immunogen Region: | Gln24-Thr98 |
Immunogen: | Recombinant Human CCL13/MCP-4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln24-Thr98) of human CCL13/MCP-4 (Accession #NP_005399.1) fused with and a hFc tag at the C-terminus. |
Post Translational Modifications | One major form (form long), and two minor forms (short chain and medium chain) are produced by differential signal peptide cleavage. The medium chain is about 30-fold less active than the long chain. |
Function | Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens. |
Protein Name | C-C Motif Chemokine 13 Ck-Beta-10 Monocyte Chemoattractant Protein 4 Monocyte Chemotactic Protein 4 Mcp-4 Ncc-1 Small-Inducible Cytokine A13 Cleaved Into - C-C Motif Chemokine 13 - Long Chain - C-C Motif Chemokine 13 - Medium Chain - C-C Motif Chemokine 13 - Short Chain |
Database Links | Reactome: R-HSA-380108 Reactome: R-HSA-418594 |
Cellular Localisation | Secreted |
Alternative Protein Names | C-C Motif Chemokine 13 protein Ck-Beta-10 protein Monocyte Chemoattractant Protein 4 protein Monocyte Chemotactic Protein 4 protein Mcp-4 protein Ncc-1 protein Small-Inducible Cytokine A13 Cleaved Into - C-C Motif Chemokine 13 - Long Chain - C-C Motif Chemokine 13 - Medium Chain - C-C Motif Chemokine 13 - Short Chain protein CCL13 protein MCP4 protein NCC1 protein SCYA13 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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