產(chǎn)品詳情
簡(jiǎn)單介紹:
Human Cathepsin S protein (Active Recombinant) (C-His) (STJP000955)
詳情介紹:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Active Recombinant-Human Cathepsin S-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of 50mM MES, 100mM NaCl, pH6.5. Contact us for customized product form or formulation. |
Immunoreactivity: | Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK (Dnp)-NH2. The specific activity is >1390 pmol/min/Mu g. |
Gene Symbol: | CTSS |
Gene ID: | 1520 |
Uniprot ID: | CATS_HUMAN |
Immunogen Region: | Gln17-Ile331 |
Immunogen: | Recombinant Human Cathepsin S Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln17-Ile331) of human Cathepsin S/CTSS (Accession #NP_004070.3) fused with an 8×His tag at the C-terminus. |
Function | Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L. |
Protein Name | Cathepsin S |
Database Links | Reactome: R-HSA-1236977 Reactome: R-HSA-1474228 Reactome: R-HSA-1679131 Reactome: R-HSA-2022090 Reactome: R-HSA-2132295 Reactome: R-HSA-6798695 |
Cellular Localisation | Lysosome Secreted Cytoplasmic Vesicle Phagosome |
Alternative Protein Names | Cathepsin S protein CTSS protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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