產(chǎn)品詳情
簡單介紹:
Human Cathepsin E protein (Recombinant) (C-His) (STJP002069)
詳情介紹:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human Cathepsin E-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a 0.2 Mu m filtered solution of 20mM MES, 150mM NaCl, pH 5.5. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CTSE |
Gene ID: | 1510 |
Uniprot ID: | CATE_HUMAN |
Immunogen Region: | Ser20-Pro396 |
Immunogen: | Recombinant Human Cathepsin E Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Ser20-Pro396) of human CTSE (Accession #P14091) fused with a 6xHis tag at the C-terminus. |
Post Translational Modifications | Glycosylated. The nature of the carbohydrate chain varies between cell types. In fibroblasts, the proenzyme contains a high mannose-type oligosaccharide, while the mature enzyme contains a complex-type oligosaccharide. In erythrocyte membranes, both the proenzyme and mature enzyme contain a complex-type oligosaccharide. Two forms are produced by autocatalytic cleavage, form I begins at Ile-54, form II begins at Thr-57. |
Function | May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain. |
Protein Name | Cathepsin E Cleaved Into - Cathepsin E Form I - Cathepsin E Form Ii |
Database Links | Reactome: R-HSA-2132295 |
Cellular Localisation | Endosome The Proenzyme Is Localized To The Endoplasmic Reticulum And Golgi Apparatus While The Mature Enzyme Is Localized To The Endosome |
Alternative Protein Names | Cathepsin E Cleaved Into - Cathepsin E Form I - Cathepsin E Form Ii protein CTSE protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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