產(chǎn)品詳情
簡單介紹:
Human B7-H2/ICOSLG/CD275 protein (Recombinant) (C-His & Avi) {Biotin} (STJP002253)
詳情介紹:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human B7-H2/ICOSLG/CD275-C-His & Avi protein was developed from hek293 cells and has a target region of C-His & Avi. For use in research applications. |
Conjugation: | Biotin |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Endotoxin: | Less than 1EU per Mu g by the LAL method. |
Gene Symbol: | ICOSLG |
Gene ID: | 23308 |
Uniprot ID: | ICOSL_HUMAN |
Immunogen Region: | Asp19-Ser258 |
Immunogen: | Recombinant Biotinylated Human B7-H2/ICOSLG Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal.;It contains Asp19-Ser258. |
Function | Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion.induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. |
Protein Name | Icos Ligand B7 Homolog 2 B7-H2 B7-Like Protein Gl50 B7-Related Protein 1 B7rp-1 Cd Antigen Cd275 |
Database Links | Reactome: R-HSA-388841 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative Protein Names | Icos Ligand protein B7 Homolog 2 protein B7-H2 protein B7-Like Protein Gl50 protein B7-Related Protein 1 protein B7rp-1 protein Cd Antigen Cd275 protein ICOSLG protein B7H2 protein B7RP1 protein ICOSL protein KIAA0653 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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