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產(chǎn)品詳情

  • 產(chǎn)品名稱：Human Apolipoprotein A-I/APOA1 protein (Recombinant) (No tag) (STJP000822)

  • 產(chǎn)品型號：STJP000822
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡單介紹：
Human Apolipoprotein A-I/APOA1 protein (Recombinant) (No tag) (STJP000822)
詳情介紹：
Host: E. coli
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Apolipoprotein A-I/APOA1-No tag protein was developed from e. coli and has a target region of No tag. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Gene Symbol: APOA1
Gene ID: 335
Uniprot ID: APOA1_HUMAN
Immunogen: Recombinant Human Apolipoprotein A-I/APOA1 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Asp25-Gln267) of human Apolipoprotein A-I (Accession #NP_000030.1).
Tissue Specificity Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. The oxidized form at Met-110 and Met-136 is increased in individuals with increased risk for coronary artery disease, such as in carrier of the eNOSa/b genotype and exposure to cigarette smoking. It is also present in increased levels in aortic lesions relative to native ApoA-I and increased levels are seen with increasing severity of disease.
Post Translational Modifications Glycosylated. Palmitoylated. Phosphorylation sites are present in the extracellular medium.
Function Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.
Protein Name Apolipoprotein A-I
Apo-Ai
Apoa-I
Apolipoprotein A1 Cleaved Into - Proapolipoprotein A-I
Proapoa-I - Truncated Apolipoprotein A-I
Apolipoprotein A-I(1-242
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-1369062
Reactome: R-HSA-1989781
Reactome: R-HSA-2168880
Reactome: R-HSA-3000471
Reactome: R-HSA-3000480
Reactome: R-HSA-381426
Reactome: R-HSA-5682113
Reactome: R-HSA-8957275
Reactome: R-HSA-8963888
Reactome: R-HSA-8963896
Reactome: R-HSA-8963901
Reactome: R-HSA-8964011
Reactome: R-HSA-8964058
Reactome: R-HSA-9707616
Reactome: R-HSA-975634
Reactome: R-HSA-977225
Cellular Localisation Secreted
Alternative Protein Names Apolipoprotein A-I protein
Apo-Ai protein
Apoa-I protein
Apolipoprotein A1 Cleaved Into - Proapolipoprotein A-I protein
Proapoa-I - Truncated Apolipoprotein A-I protein
Apolipoprotein A-I(1-242 protein
APOA1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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