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產(chǎn)品詳情

  • 產(chǎn)品名稱：Anti-ACAP1 antibody (490-570) (STJA0010088)

  • 產(chǎn)品型號(hào)：STJA0010088
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
Anti-ACAP1 antibody (490-570) (STJA0010088)
詳情介紹：
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (490-570) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ACAP1
Gene ID: 9744
Uniprot ID: ACAP1_HUMAN
Immunogen Region: 490-570
Specificity: This antibody detects endogenous levels of Human Centaurin-Beta 1
Immunogen: Synthesized peptide derived from human Centaurin-Beta 1 AA range: 490-570
Tissue Specificity Highest level in lung and spleen. Low level in heart, kidney, liver and pancreas.
Post Translational Modifications Phosphorylation at Ser-554 by PKB is required for interaction with ITGB1, export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.
Function GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.
Protein Name Arf-Gap With Coiled-Coil - Ank Repeat And Ph Domain-Containing Protein 1
Centaurin-Beta-1
Cnt-B1
Cellular Localisation Recycling Endosome Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Alternative Antibody Names Anti-Arf-Gap With Coiled-Coil - Ank Repeat And Ph Domain-Containing Protein 1 antibody
Anti-Centaurin-Beta-1 antibody
Anti-Cnt-B1 antibody
Anti-ACAP1 antibody
Anti-CENTB1 antibody
Anti-KIAA0050 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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