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產(chǎn)品詳情

  • 產(chǎn)品名稱：Human B29/CD79B protein (Recombinant) (C-His & Avi) {Biotin} (STJP002118)

  • 產(chǎn)品型號：STJP002118-100
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡單介紹：
Human B29/CD79B protein (Recombinant) (C-His & Avi) {Biotin} (STJP002118)
詳情介紹：
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human B29/CD79B-C-His & Avi protein was developed from hek293 cells and has a target region of C-His & Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity: Immobilized Biotinylated Human CD79b, His Tag at 0.5 Mu g/mL (100 Mu L/Well).Dose response curve for Anti-CD79b Ab. with the EC50 of 11.3 ng/mL determined by ELISA.
Gene Symbol: CD79B
Gene ID: 974
Uniprot ID: CD79B_HUMAN
Immunogen Region: Ala29-Asp159
Immunogen: Biotinylated Recombinant Human CD79B Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Ala29-Asp159) of Human CD79B fused with a His tag and Avi tag at theC-terminal.
Post Translational Modifications Phosphorylated on tyrosine upon B-cell activation by SRC-type Tyr-kinases such as BLK, LYN and SYK.
Function Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
Protein Name B-Cell Antigen Receptor Complex-Associated Protein Beta Chain
B-Cell-Specific Glycoprotein B29
Ig-Beta
Immunoglobulin-Associated B29 Protein
Cd Antigen Cd79b
Database Links Reactome: R-HSA-5690714
Reactome: R-HSA-9679191
Reactome: R-HSA-983695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Following Antigen Binding
The Bcr Has Been Shown To Translocate From Detergent-Soluble Regions Of The Cell Membrane To Lipid Rafts Although Signal Transduction Through The Complex Can Also Occur Outside Lipid Rafts
Alternative Protein Names B-Cell Antigen Receptor Complex-Associated Protein Beta Chain protein
B-Cell-Specific Glycoprotein B29 protein
Ig-Beta protein
Immunoglobulin-Associated B29 Protein protein
Cd Antigen Cd79b protein
CD79B protein
B29 protein
IGB protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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