產(chǎn)品詳情
簡單介紹：
Anti-ABCB10 antibody (C-Term) (STJ71629)
詳情介紹：
| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Goat polyclonal antibody anti-ABCB10 (C-Term) is suitable for use in ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | ELISA-antibody detection limit dilution 1:64000. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | ABCB10 |
| Gene ID: | 23456 |
| Uniprot ID: | ABCBA_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_036221.2 |
| Immunogen Sequence: | KPNGIYRKLMNKQ |
| Function | Catalyzes the export of an unknown physiological substrate from the mitochondrial matrix to the cytosol in an ATP-dependent manner. May also transport the heme analog Zn (II) mesoporphyrin (ZnMP) in an ATP dependent manner but can't export the heme precursor 5-aminolevulinic acid (ALA) from mitochondria. Plays a role in the early step of the heme biosynthetic process during insertion of iron into protoporphyrin IX (PPIX). In turn participates in hemoglobin synthesis and also protects against oxidative stress. In addition may be involved in mitochondrial unfolded protein response (UPRmt) signaling pathway, although ABCB10 probably does not participate in peptide export from mitochondria. |
| Protein Name | Atp-Binding Cassette Sub-Family B Member 10 - Mitochondrial Abc-Mitochondrial Erythroid Protein Abc-Me Protein Atp-Binding Cassette Transporter 10 Abc Transporter 10 Protein Mitochondrial Atp-Binding Cassette 2 M-Abc2 |
| Database Links | Reactome: R-HSA-1369007 |
| Cellular Localisation | Mitochondrion Inner Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Atp-Binding Cassette Sub-Family B Member 10 - Mitochondrial antibody Anti-Abc-Mitochondrial Erythroid Protein antibody Anti-Abc-Me Protein antibody Anti-Atp-Binding Cassette Transporter 10 antibody Anti-Abc Transporter 10 Protein antibody Anti-Mitochondrial Atp-Binding Cassette 2 antibody Anti-M-Abc2 antibody Anti-ABCB10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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