產(chǎn)品詳情
簡單介紹：
Anti-ABCB10 antibody (441-490 aa) (STJ91410)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-ATP-binding cassette sub-family B member 10, mitochondrial (441-490 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:40000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ABCB10 |
| Gene ID: | 23456 |
| Uniprot ID: | ABCBA_HUMAN |
| Immunogen Region: | 441-490 aa |
| Specificity: | ABCB10 Polyclonal Antibody detects endogenous levels of ABCB10 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ABCB10 at the amino acid range 441-490 |
| Function | Catalyzes the export of an unknown physiological substrate from the mitochondrial matrix to the cytosol in an ATP-dependent manner. May also transport the heme analog Zn (II) mesoporphyrin (ZnMP) in an ATP dependent manner but can't export the heme precursor 5-aminolevulinic acid (ALA) from mitochondria. Plays a role in the early step of the heme biosynthetic process during insertion of iron into protoporphyrin IX (PPIX). In turn participates in hemoglobin synthesis and also protects against oxidative stress. In addition may be involved in mitochondrial unfolded protein response (UPRmt) signaling pathway, although ABCB10 probably does not participate in peptide export from mitochondria. |
| Protein Name | Atp-Binding Cassette Sub-Family B Member 10 - Mitochondrial Abc-Mitochondrial Erythroid Protein Abc-Me Protein Atp-Binding Cassette Transporter 10 Abc Transporter 10 Protein Mitochondrial Atp-Binding Cassette 2 M-Abc2 |
| Database Links | Reactome: R-HSA-1369007 |
| Cellular Localisation | Mitochondrion Inner Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Atp-Binding Cassette Sub-Family B Member 10 - Mitochondrial antibody Anti-Abc-Mitochondrial Erythroid Protein antibody Anti-Abc-Me Protein antibody Anti-Atp-Binding Cassette Transporter 10 antibody Anti-Abc Transporter 10 Protein antibody Anti-Mitochondrial Atp-Binding Cassette 2 antibody Anti-M-Abc2 antibody Anti-ABCB10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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