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產(chǎn)品詳情

  • 產(chǎn)品名稱：Anti-ABCB10 antibody (230-300) (STJ115732)

  • 產(chǎn)品型號(hào)：STJ115732
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
Anti-ABCB10 antibody (230-300) (STJ115732)
詳情介紹：
Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ABCB10 (230-300) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ABCB10
Gene ID: 23456
Uniprot ID: ABCBA_HUMAN
Immunogen Region: 230-300
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 230-300 of human ABCB10 (NP_036221.2).
Immunogen Sequence: AIRVYLMQTSGQRIVNRLRT SLFSSILRQEVAFFDKTRTG ELINRLSSDTALLGRSVTEN LSDGLRAGAQA
Tissue Specificity Ubiquitous. Highly expressed in bone marrow, expressed at intermediate to high levels in skeletal muscle, small intestine, thyroid, heart, brain, placenta, liver, pancreas, prostate, testis, ovary, leukocyte, stomach, spinal cord, lymph node, trachea and adrenal gland, and low levels are found in lung, kidney, spleen, thymus and colon.
Function Catalyzes the export of an unknown physiological substrate from the mitochondrial matrix to the cytosol in an ATP-dependent manner. May also transport the heme analog Zn (II) mesoporphyrin (ZnMP) in an ATP dependent manner but can't export the heme precursor 5-aminolevulinic acid (ALA) from mitochondria. Plays a role in the early step of the heme biosynthetic process during insertion of iron into protoporphyrin IX (PPIX). In turn participates in hemoglobin synthesis and also protects against oxidative stress. In addition may be involved in mitochondrial unfolded protein response (UPRmt) signaling pathway, although ABCB10 probably does not participate in peptide export from mitochondria.
Protein Name Atp-Binding Cassette Sub-Family B Member 10 - Mitochondrial
Abc-Mitochondrial Erythroid Protein
Abc-Me Protein
Atp-Binding Cassette Transporter 10
Abc Transporter 10 Protein
Mitochondrial Atp-Binding Cassette 2
M-Abc2
Database Links Reactome: R-HSA-1369007
Cellular Localisation Mitochondrion Inner Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Atp-Binding Cassette Sub-Family B Member 10 - Mitochondrial antibody
Anti-Abc-Mitochondrial Erythroid Protein antibody
Anti-Abc-Me Protein antibody
Anti-Atp-Binding Cassette Transporter 10 antibody
Anti-Abc Transporter 10 Protein antibody
Anti-Mitochondrial Atp-Binding Cassette 2 antibody
Anti-M-Abc2 antibody
Anti-ABCB10 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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