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產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：Aquaporin 7 Blocking Peptide peptide (STJ503667)

  • 產(chǎn)品型號(hào)：STJ503667-250
  • 產(chǎn)品廠(chǎng)商：ST john's laboratory
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
Aquaporin 7 Blocking Peptide peptide (STJ503667)
詳情介紹：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Aquaporin 7 Blocking Peptide is synthetically produced from the 150-200 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Aqp7
Gene ID: 11832
Uniprot ID: AQP7_MOUSE
Immunogen Region: 150-200
Immunogen: Synthetic amidated peptide taken within amino acid region 150-200 on rat Aquaporin 7 protein, covalently modified and conjugated to KLH.
Tissue Specificity Detected in proximal tubules in kidney. Detected in the capillary network between muscle fibers in skeletal muscle and heart, and in spermatids and on spermatozoa tails in testis and epididymis. Detected in white and brown adipose tissue, especially on small blood vessels (at protein level). Detected in kidney and white adipose tissue.
Function Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH. The channel is also permeable to urea. Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids. Mediates glycerol export from adipocytes. After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia. Required for normal glycerol reabsorption in the kidney.
Peptide Name Aquaporin-7
Aqp-7
Aquaglyceroporin-7
Database Links Reactome: R-MMU-432030
Reactome: -MMU-432047
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cytoplasm
Cell Cortex
Cytoplasmic Vesicle Membrane
Lipid Droplet
Internalized From The Cell Membrane In Response To Catecholamine-Induced Activation Of Pka
Detected On Intracellular Membranes And Colocalizes With Lipid Droplets
Colocalizes With Plin1 In Adipocytes
Probably On Lipid Droplets
Alternative Peptide Names Aquaporin-7 protein
Aqp-7 protein
Aquaglyceroporin-7 protein
Aqp7 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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