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產(chǎn)品詳情
  • 產(chǎn)品名稱:Alsin (ALS2) Antibody

  • 產(chǎn)品型號:abx003718
  • 產(chǎn)品廠商:abbexa
  • 產(chǎn)品文檔:
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簡單介紹:
Alsin (ALS2) Antibody
詳情介紹:
ALS2 Antibody is a Rabbit Polyclonal antibody against ALS2. The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.

Target Alsin (ALS2)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ALS2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q96Q42 (UniProt, ExPASy)
UniProt Secondary AC Q53TT1, Q53TV2, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9
UniProt Entry Name ALS2_HUMAN
Gene Symbol ALS2
GeneID 57679
NCBI Accession NP_065970.2
KEGG hsa:57679
String 9606.ENSP00000264276
Molecular Weight Calculated MW: 184 kDa
Observed MW: 174 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Alsin (ALS2)
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