Alpha Adducin (ADD1) Antibody is a Rabbit Polyclonal against Alpha Adducin (ADD1). Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C.

Target	Alpha Adducin (ADD1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	ELISA: 1/10000, IHC: 1/100 - 1/300, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Synthesized peptide derived from human Adducin α around the non-phosphorylation site of T445.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P35611 (UniProt, ExPASy) Q9QYC0 (UniProt, ExPASy)
UniProt Entry Name	ADDA_HUMAN, ADDA_MOUSE
Gene Symbol	ADD1
GeneID	118
OMIM	102680
NCBI Accession	NP_001110.2 NM_001119.4
HGNC	243
Ensembl	ENSG00000087274
String	9606.ENSP00000264758 10090.ENSMUSP00000109979
Buffer	PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Alpha Adducin (ADD1)