SERPINA3 Antibody is a Rabbit Polyclonal antibody against SERPINA3. The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008].

Target	Alpha-1-Antichymotrypsin (SERPINA3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 24-423 of human Alpha-1 Antichymotrypsin (SERPINA3).
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P01011 (UniProt, ExPASy)
UniProt Secondary AC	B3KVQ7, Q13703, Q2TU87, Q2TU88, Q59GP9, Q6LBY8, Q6LDT7, Q6NSC9, Q8N177, Q96DW8, Q9UC47, Q9UNU9
UniProt Entry Name	AACT_HUMAN
Gene Symbol	SERPINA3
GeneID	12
OMIM	107280
NCBI Accession	NP_001076.2 NM_001085.4
HGNC	16
KEGG	hsa:12
Ensembl	ENSG00000196136
String	9606.ENSP00000450540
Molecular Weight	Calculated MW: 48 kDa Observed MW: 50-76 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	0.3 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Alpha-1-Antichymotrypsin (SERPINA3)