ADH5 is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis.

Target	Alcohol Dehydrogenase Class-3 (ADH5)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/4000, IHC-P: 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 212-239 amino acids from the Central region of human ADH5.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P11766 (UniProt, ExPASy)
UniProt Secondary AC	Q6FHR2
UniProt Entry Name	ADHX_HUMAN
KEGG	hsa:128
String	9606.ENSP00000296412
Molecular Weight	Calculated MW: 39.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rabbit ADH5.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Alcohol Dehydrogenase Class-3 (ADH5)