Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression.

Target	Acidic Leucine-Rich Nuclear Phosphoprotein 32 Family Member A (ANP32A)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/2000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 133-162 amino acids from the Central region of human ANP32A.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P39687 (UniProt, ExPASy)
UniProt Secondary AC	B2R6T4, Q53FK4, Q5J8L8, Q7M4N6
UniProt Entry Name	AN32A_HUMAN
Gene Symbol	ANP32A
KEGG	hsa:8125
String	9606.ENSP00000417864
Molecular Weight	Calculated MW: 28.6 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow and Xenopus ANP32A.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Acidic Leucine-Rich Nuclear Phosphoprotein 32 Family Member A (ANP32A)