Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. ALDH3A1 forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. The enzyme is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea.

Target	Aldehyde Dehydrogenase 3 Family Member A1 (ALDH3A1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 254-284 amino acids from the Central region of human ALDH3A1.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P30838 (UniProt, ExPASy)
UniProt Secondary AC	A8K828, Q9BT37
UniProt Entry Name	AL3A1_HUMAN
NCBI Accession	NP_000682.3 NP_001128639.1 NP_001128640.1
KEGG	hsa:218
String	9606.ENSP00000411821
Molecular Weight	Calculated MW: 50.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow ALDH3A1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Aldehyde Dehydrogenase 3 Family Member A1 (ALDH3A1)