PTS Antibody is a Rabbit Polyclonal antibody against PTS. The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia.

Target	6-Pyruvoyl Tetrahydrobiopterin Synthase (PTS)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human PTS.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q03393 (UniProt, ExPASy)
UniProt Secondary AC	B0YJ87, Q8WVG8
UniProt Entry Name	PTPS_HUMAN
Gene Symbol	PTS
GeneID	5805
OMIM	261640
NCBI Accession	NP_000308.1
HGNC	9689
KEGG	hsa:5805
Ensembl	ENSG00000150787
String	9606.ENSP00000280362
Molecular Weight	Calculated MW: 16 kDa Observed MW: 16 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 6-Pyruvoyl Tetrahydrobiopterin Synthase (PTS)