26S Proteasome Non-ATPase Regulatory Subunit 13 (PSMD13) Antibody is a Rabbit Polyclonal against 26S Proteasome Non-ATPase Regulatory Subunit 13 (PSMD13). The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described.

Target	26S Proteasome Non-ATPase Regulatory Subunit 13 (PSMD13)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/5000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant human 26S proteasome non-ATPase regulatory subunit 13 protein (1-250AA).
Isotype	IgG
Form	Liquid
Purification	Antigen Affinity Chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UNM6 (UniProt, ExPASy)
UniProt Secondary AC	B3KT15, O75831, Q53XU2, Q9UNV3
UniProt Entry Name	PSD13_HUMAN
Gene Symbol	PSMD13
GeneID	5719
OMIM	603481
NCBI Accession	NP_002808.3 NM_002817.3 NP_787128.2 NM_175932.2
HGNC	9558
Ensembl	ENSG00000185627
Buffer	PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 13 (PSMD13)