26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11) Antibody (HRP) is a Rabbit Polyclonal antibody against 26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11) conjugated to HRP. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene.

Target	26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA
Host	Rabbit
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Conjugation	HRP
Immunogen	Recombinant human 26S proteasome non-ATPase regulatory subunit 11 protein (2-422AA).
Isotype	IgG
Form	Liquid
Purity	> 95%
Purification	Purified by Protein G.
Storage	Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O00231 (UniProt, ExPASy)
UniProt Secondary AC	A8K3I7, E1P663, O00495, Q53FT5
UniProt Entry Name	PSD11_HUMAN
Gene Symbol	PSMD11
GeneID	5717
OMIM	604449
NCBI Accession	NP_001257411.1 NM_001270482.1
HGNC	9556
KEGG	hsa:5717
Ensembl	ENSG00000108671
String	9606.ENSP00000261712
Buffer	0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11)