Galactocerebrosides are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system and are also present in small amounts in kidney. The key enzymatic step in the biosynthesis of galactocerebrosides consists of the transfer of galactose to ceramide catalyzed by UDP-galactose ceramide galactosyltransferase (CGT, EC 2.4.1.45). The enzyme encoded by the CGT gene is the first involved in complex lipid biosynthesis in the myelinating oligodendrocyte.[supplied by OMIM].

Target	2-Hydroxyacylsphingosine 1-Beta-Galactosyltransferase (UGT8)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 366-393 amino acids from the Central region of human UGT8.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q16880 (UniProt, ExPASy)
UniProt Secondary AC	B3KXU7, O00196
UniProt Entry Name	CGT_HUMAN
KEGG	hsa:7368
String	9606.ENSP00000311648
Molecular Weight	Calculated MW: 61.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rat UGT8.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 2-Hydroxyacylsphingosine 1-Beta-Galactosyltransferase (UGT8)