This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product.

This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product.

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.

Target	14-3-3 Protein Sigma (SFN)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 120-149 amino acids from the Central region of human SFN.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P31947 (UniProt, ExPASy)
UniProt Secondary AC	Q6FH30, Q6FH51, Q96DH0
UniProt Entry Name	1433S_HUMAN
Gene Symbol	SFN
NCBI Accession	NP_006133.1
KEGG	hsa:2810
String	9606.ENSP00000340989
Molecular Weight	Calculated MW: 27.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Cow SFN.
Availability	Please enquire.
Note	This product is for research use only.

Research Articles on 14-3-3 Protein Sigma (SFN)