YWHAG belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.

Target	14-3-3 Protein Gamma (YWHAG)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 136-164 amino acids from the Central region of human YWHAG.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P61981 (UniProt, ExPASy)
UniProt Secondary AC	O70457, P35214, Q6FH52, Q9UDP2, Q9UN99
UniProt Entry Name	1433G_HUMAN
KEGG	hsa:7532
String	9606.ENSP00000306330
Molecular Weight	Calculated MW: 28.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rat, Cow, Chicken, Sheep and Xenopus YWHAG.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 14-3-3 Protein Gamma (YWHAG)