PSMD7 Antibody is a Rabbit Polyclonal antibody against PSMD7. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.

Target	26S Proteasome Non-ATPase Regulatory Subunit 7 (PSMD7)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-324 of human PSMD7.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P51665 (UniProt, ExPASy)
UniProt Secondary AC	D3DWS9, Q6PKI2, Q96E97
UniProt Entry Name	PSMD7_HUMAN
Gene Symbol	PSMD7
GeneID	5713
OMIM	157970
NCBI Accession	NP_002802.2
HGNC	9565
KEGG	hsa:5713
Ensembl	ENSG00000103035
String	9606.ENSP00000219313
Molecular Weight	Calculated MW: 37 kDa Observed MW: 37 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 7 (PSMD7)