PSMD7 Antibody is a Rabbit Polyclonal against PSMD7. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.

Target	26S Proteasome Non-ATPase Regulatory Subunit 7 (PSMD7)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/5000, IHC: 1/500 - 1/1000, IF/ICC: 1/50 - 1/500, IP: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant human 26S proteasome non-ATPase regulatory subunit 7 protein (1-324AA).
Isotype	IgG
Form	Liquid
Purity	> 95%
Purification	Purified by Protein G.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P51665 (UniProt, ExPASy)
UniProt Secondary AC	D3DWS9, Q6PKI2, Q96E97
UniProt Entry Name	PSMD7_HUMAN
Gene Symbol	PSMD7
GeneID	5713
OMIM	157970
HGNC	9565
KEGG	hsa:5713
Ensembl	ENSG00000103035
String	9606.ENSP00000219313
Buffer	0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 7 (PSMD7)